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Liprojeke tsa rona tsa lipatlisiso tsa EB

DEBRA UK ke motšehetsi e moholo oa UK oa EB lipatlisiso, ho fana ka lithuso ho bafuputsi ba nang le litsebo tsa saense le tsa bongaka tse amanang haholo le malapa a phelang le EB.

Mesebetsi ea rona ea merero ea lipatlisiso e kenyelletsa liteko tsa tleliniki, mosebetsi oa laboratori ea pele ho moo, lipatlisiso tsa liphatsa tsa lefutso le lisele le ho sebelisa lithethefatsi hape, hammoho le merero e tsamaisang phetoho ea ho folisa mats'oao le kalafo ea mofetše.

Lipatlisiso tseo re li tšehetsang ka lichelete ke tsa maemo a lefats'e, 'me ke hobane ha re tšehetse bo-ramahlale le lingaka tsa UK feela empa ba ipabola ka ho fetisisa lefatšeng. Re boetse re ikemiseditse ho tshehetsa moloko o latelang wa bafuputsi ba EB e le letsete la bokamoso ba dipatlisiso tsa EB. Boholo ba merero eo re e tšehetsang ka lichelete e kopanya tsebo le bokhoni bo tsoang ho bafuputsi libakeng tse ngata tsa lipatlisiso UK le linaheng tse ling.

Rasaense ea apereng seaparo sa lab le liatlana tse putsoa o sebelisa pipette ea multichannel ho fetisetsa mokelikeli ka har'a microplate.

PhD: ho loantša mofetše oa letlalo oa RDEB

Moprofesa Gareth Inman, Patlisiso ea Kankere UK Scotland Institute, UK
Ithute haholoanyane
Setšoantšo sa kokoana-hloko e nang le khetla e rarahaneng ea ka ntle le sebopeho sa DNA se bonahalang, se totobatsang phephetso e rarahaneng e tobaneng le phekolo ea lefu la moea, e pota-potiloeng ke likaroloana tse tšoanang tsa kokoana-hloko mokokotlong o khanyang.

PhD: Phekolo ea mRNA bakeng sa JEB

Mop McCarthy, Univesithi ea Mofumahali, Belfast
Ithute haholoanyane
Setšoantšo sa karolo e fapaneng ea letlalo la motho, le nang le masela a bonahalang, lisosa tsa moriri, methapo ea mali, le sebaka se sefubelu se benyang se pota-potileng leqeba.

PhD: ho eketsa YAP / TAZ ho potlakisa pholiso ea maqeba

Ngaka Gernot Walko, QMUL, UK
Ithute haholoanyane
Boemo bo haufi-ufi ba lesea le robetseng fatše, le shebile holimo, le tsepamisitse maikutlo mahlong le li-eyelashes tse telele.

PhD: ho fokotsa leqeba la mahlo la DEB/JEB

Moprofesa Keith Martin, CERA, Univesithi ea Melbourne, Australia
ITHUTE HAHOLOANYANE
Mofuputsi ea apereng liatlana tse putsoa o beha sejana sa Petri tlas'a microscope bakeng sa tlhahlobo.

PhD: ho fokotsa likhahla ho JEB

Ngaka Emma Chambers, QMUL, UK
Ithute haholoanyane
Motho ea apereng liatlana tse putsoa o sebelisa pipette ho fetisetsa mokelikeli o mofubelu ka har'a poleiti e nang le liliba tse ngata, e nang le lisebelisoa tsa laborateng le lijana ka morao.

PhD: ho ntlafatsa ho lokisoa ha letlalo ho JEB

Ngaka Emanuel Rognoni, QMUL, UK
Ithute haholoanyane
Setshwantsho sa tlhale ya DNA e hokahanang le dimolekhule tse kgolokwe tse tala, tse behilweng kgahlanong le bokamorao bo kganyang.

PhD: thuto ea maqeba a nanoneedle ho RDEB

Moprofesa John McGrath, KCL, UK
Ithute haholoanyane
Setšoantšo se bontšang methati ea ho fola ha maqeba: ho hoama ka lekhoakhoa, ho ikatisa ha lisele, le ho khutlisa lisele ka phepelo ea mali. Li-labels li kenyelletsa epidermis, dermis, fibroblast, le macrophage.

PhD: pholiso ea maqeba ka mefuta eohle ea EB (2024)

Moprofesa Adrian Heagerty le Ngaka Ajoy Bardhan, Univesithi ea Birmingham, UK
Ithute haholoanyane
Papiso e qaqileng ea anatomical e bontšang molala oa motho o nang le trachea, bronchi, le methapo ea mali e potolohileng le methapo, e totobatsang kamoo li-biofilms li ka liehisang pholiso ea leqeba la EB.

Phekolo ea lefu la moea ho JEB

Ngaka Robert Hynds, Univesithing ea London, UK
Ithute haholoanyane
Motho ea apereng jase ea lab o tšoere serinji e nang le nale e eme holimo.

Repurposing dupilumab ho phekola ho hlohlona ka mefuta eohle ea EB

Moporof Amy Paller, Yunibesiti ya Bokone Bophirima, USA
Ithute haholoanyane
Setšoantšo sa motho ea tšoereng letlapa letsohong.

Matlapa a Psoriasis a rekiselitsoe hape bakeng sa EBS

Ngaka Christine Chiaverini, Center Hospitaler Universitaire de Nice, Fora
Ithute haholoanyane
Buka ea ho ngolla lintlha, lintlha tse khomarelang, le laptop li lutse ka thōko ho leqephe le bontšang lichate tse mebala-bala le kerafo tafoleng.

Ho lula le EB UK

Ngaka Zoe Venables, Univesithi ea East Anglia, UK
Ithute haholoanyane
Ngoana ea bososelang ea apereng mapheo a serurubele a maputsoa o tšoere sekoahelo sa serurubele se pinki se matheba a polka ka pel'a lemati le turquoise.

Ho phekola JEB ka protheine ea laminin

Ngaka Matthew Caley, QMUL, UK
Ithute haholoanyane
Ngoana ka ho bapala o sebelisa khaba ho sheba molomo o bulehileng oa motho e moholo. Bobeli ba ka tlung, ba lutse sofeng.

DEB kankere le pholiso ea leqeba la molomo

Ngaka Inês Sequeira, QMUL, UK
Ithute haholoanyane
Likonopo tse hlano tsa keyboard mopeleto "PASTE" li hlophisitsoe ka bokamorao bo bofubelu.

Phekolo ea kamehla ea lefutso bakeng sa DEB

Ngaka Joanna Jacków, KCL, UK
Ithute haholoanyane
Rakhemisi o hlahloba botlolo ea meriana shelofong e tletseng lihlahisoa tse fapa-fapaneng tsa meriana.

Ho khutlisetsa li-statins bakeng sa mofetše oa letlalo oa RDEB

Ngaka Roland Zauner, EB House, Austria
Ithute haholoanyane
Lelapa le bososela le shebile k'hamera. Moshanyana e mong o apere sekipa sa DEBRA se pherese

Setsi sa lisebelisoa tsa bophelo bo botle bakeng sa batsoali bohle ba EB

Moprofesa Andrew Thompson, Univesithi ea Cardiff, UK
Ithute haholoanyane
Maoto a haufi a lesea a lutseng letsohong la motho e moholo ea nang le lipekere tse pentiloeng tse ntšo, tse behiloeng khahlanong le mokokotlo o bonolo, o lerootho.

Phekolo e ntlafalitsoeng ea blister bakeng sa EBS

Mop John Connelly, QMUL, UK
Ithute haholoanyane
E haufi-ufi ea leihlo le nang le iris e sootho, li-eyelashes tse telele, le khanya ea leseli holim'a thaka.

Marotholi a mahlo a mefuta eohle ea EB

Moprofesa Liam Grover, Univesithi ea Birmingham, UK
Ithute haholoanyane
Motho ea tšoereng poleiti e bonaletsang ea liliba tse 96 e nang le maro a mebala e fapaneng sebakeng sa laboratoring.

Ho hlahloba lithethefatsi ho lebisa mofetše oa RDEB

Moprofesa Gareth Inman, Setsi sa CRUK Scotland, UK
Ithute haholoanyane
Setšoantšo se bonts'ang boikitlaetso bo tsamaisoang ke mokuli ba ho etsa lipatlisiso tsa meriana e thehiloeng ho cannabinoid bakeng sa bohloko le ho hlohlona ho EB, e nang le boko, letlalo le lekhasi la cannabis hammoho le boiteko ba PhD bo shebaneng le ho ntlafatsa tokiso ea letlalo ho JEB.

Kalafo ea Cannabinoid bakeng sa bohloko bohle ba EB le ho hlohlona (2024)

Mop Ngaka André Wolff le Ngaka Marieke Bolling, Setsi sa Bongaka sa Univesithi Groningen, Netherlands
Ithute haholoanyane
Papiso ea motho ea chesitsoeng ke letsatsi mokokotlong, ea emeng tlas'a khanya ea letsatsi. Letlalo le bontša mekhoa ea hexagonal, e totobatsang ho pepeseha ha letsatsi le phello ea mocheso.

KEB le mofetše oa letlalo (2024)

Moprofesa Valerie Brunton, Univesithi ea Edinburgh, UK
Ithute haholoanyane

Ho khutlisetsa lithethefatsi tse thibelang maqeba ho RDEB (2023)

Ngaka Daniele Castiglia, Istituto Dermopatico dell'Immacolata, IRCCS, Italy
Ithute haholoanyane
Setšoantšo sa monna ea nang le sebaka se totobetseng se bontšang squamous cell carcinoma phatleng ea hae le leqeba le haufi le letlalo.

Kankere ea letlalo ea RDEB (2023)

Moprofesa Gareth Inman, Univesithi ea Glasgow, UK
Ithute haholoanyane

Ho fokotseha ho RDEB (2023)

Mop Giovanna Zambruno, Sepetlele sa Bana sa Bambino Gesù (IRCCS), Roma, Italy.
Ithute haholoanyane

Ho utloisisa lefu la moea ho JEB (2023)

Ngaka Colin Butler, GOSH, UK
Ithute haholoanyane

Ho kenya letsoho tsamaisong ea 'mele ea ho itšireletsa mafung ho RDEB (2023)

Ngaka Yanling Liao, NYMC, USA
Ithute haholoanyane

Microbiome ea letlalo ea mefuta eohle ea EB (2023)

Mop Iain Chapple, Sekolo sa Meno sa Birmingham le Sepetlele, UK
Ithute haholoanyane

Fafatsa ka phekolo ea lefutso ea RDEB (2022)

Ngaka Su Lwin, KCL, UK
Ithute haholoanyane

Thuto ea matšoao a PEBLES RDEB (2022)

Mop Jemima Mellerio, Setsi sa St John sa Dermatology le GOSH, London
Ithute haholoanyane

Ho tsamaea le EBS (2022)

Ngaka Deborah Falla le Moprofesa Adrian Heagerty, Univesithi ea Birmingham, UK
Ithute haholoanyane

Kalafo ea ho fafatsa molomo/metso (2022)

Moprofesa Liam Grover, Univesithi ea Birmingham, UK
Ithute haholoanyane

Rigosertib bakeng sa RDEB SSC (2022)

Ngaka Andrew South, Thomas Jefferson University, USA
Ithute haholoanyane

Lisele tsa 'mele oa ho itšireletsa mafung le maqeba a RDEB (2022)

Mop Ngaka Sabine Eming, Sepetlele sa Univesithi ea Cologne, Jeremane
Ithute haholoanyane

Ho phekola DEB itch ka lisele tsa stem (2022)

Mop John McGrath le Mop Jemima Mellerio, KCL, UK
Ithute haholoanyane

Phekolo ea liphatsa tsa lefutso bakeng sa EBS le RDEB (2022)

Ngaka Robyn Hickerson le Ngaka Peter van den Akker, Univesithi ea Dundee, UK
Ithute haholoanyane

Decorin gel ho fokotsa maqeba (2019)

Ngaka Mark de Souza le Moprofesa Jean Tang, FIBRX Derm Inc, USA
Ithute haholoanyane

LENTICOL F (2019)

Mop John McGrath, Setsi sa St John sa Dermatology le Setsi sa Bophelo bo Botle ba Bana, UK
Ithute haholoanyane

Inman-South 1 (2019)

Ngaka Gareth Inman le Dr Andrew South, Univesithi ea Dundee, UK
Ithute haholoanyane

Hickerson 1 (2019)

Ngaka Robyn Hickerson, Univesithi ea Dundee, UK
Ithute haholoanyane

McLean 12 (2019)

Moprofesara Irwin McLean le Ngaka Robyn Hickerson, Univesithi ea Dundee, UK
Ithute haholoanyane

Brunton 1 (2018)

Moprofesa Valerie Brunton, Univesithi ea Edinburgh, UK
Ithute haholoanyane

ADSTEM (2018)

Mop John McGrath, Setsi sa St John sa Dermatology, UK
Ithute haholoanyane

Roopenian 2 (2017)

Ngaka Derry Roopenian, The Jackson Laboratory, USA
Ithute haholoanyane

Tolar 3 (2017)

Moprofesa Jakub Tolar, Univesithi ea Minnesota, USA
Ithute haholoanyane

Gaggioli 2 (2017)

Ngaka Cedric Gaggioli, ADSM, Nice, Fora
Ithute haholoanyane

Bauer 5 (2017)

Mop Johann Bauer, EB House, Austria
Ithute haholoanyane

Uitto 1 (2017)

Mop Jouni Uitto, Thomas Jefferson University, USA
Ithute haholoanyane

O'Toole (2015)

Moprofesa Edel O'Toole, QMUL, UK
Ithute haholoanyane

EBSTEM (2015)

Mop John McGrath, Setsi sa St John sa Dermatology, UK
Ithute haholoanyane

Tolar 2 (2015)

Moprofesa Jakub Tolar, Univesithi ea Minnesota, USA
Ithute haholoanyane

McLean/Heagerty 1 (2014)

Mop Irwin Mclean le Moprofesa Adrian Heagerty, Univesithi ea Dundee, UK
Ithute haholoanyane

McGrath (2014)

Mop John McGrath, Sepetlele sa Guy London, UK
Ithute haholoanyane

Sonnenberg (2013)

Ngaka Arnoud Sonnenberg, The Netherlands Cancer Institute, Netherlands
Ithute haholoanyane

Borwa (2013)

Ngaka Andrew South, Thomas Jefferson University, USA
Ithute haholoanyane
Mohaho oa mehleng ea kajeno, o nang le mekato e mengata o nang le sefahleho sa khalase le letšoao le balang "Mohaho oa Lipatlisiso tsa Kankere." Ho na le mohloa o nang le joang ka pele le batho ba 'maloa haufi le monyako.

Tšebelisano: Mefuta ea mofetše ea pele ho tleliniki ea RDEB

Moprofesa Gareth Inman, Setsi sa CRUK Scotland, UK
Ithute haholoanyane
Sekwere se seputsoa se nang le logo ea NHS ka litlhaku tse tšoeu, e behiloe bokaholimo bo boputsoa bo lefifi.

NHS England Partnership: Ho utloisisa boitsebiso ba mokuli ba EB bo tšoaretsoeng ka har'a NHS

Ngaka Zoe Venables le Marta Kwiatkowska, NHS England, UK
Ithute haholoanyane
Motho ea tšoereng stethoscope haufi le letlapa le bontšang lintlha tse ngotsoeng o lutse haufi le laptop holim'a bokaholimo ba beige.

Setsi sa pele sa lipatlisiso tsa bongaka sa EB Afrika

Dr Daudi Mavura, Setsi sa Koetliso ea Dermatology ea Libaka (RDTC), Tanzania
Ithute haholoanyane
Batho ba babeli ba etsang lipatlisiso ba supa letlapa le bontšang tatellano ea litlhaku tsa DNA tse 'mala o moputsoa le o mosehla. Motho a le mong o apere jase ea lab.

Ho latela liphatsa tsa lefutso tsa EBS

Ngaka Laura Valinotto, CEDIGEA, Univesithi ea Buenos Aires, Argentina
Ithute haholoanyane
Setšoantšo sa microscopic se bonts'a baktheria e pherese e chitja sebakeng se entsoeng ka botala.

Li-biofilms li lieha ho fola ha leqeba la EB

Ngaka Josefine Hirschfeld, Univesithi ea Birmingham, UK
Ithute haholoanyane
Setšoantšo sa DNA strand e sebelisanang le bokaholimo ba graphene ba hexagonal, e bonts'ang tšebelisano ea limolek'hule mokokotlong oa grid.

Teko e nolofalitsoeng ea liphatsa tsa lefutso bakeng sa mefuta eohle ea EB

Ngaka Ene-Choo Tan, Sepetlele sa Basali le Bana sa KK, Singapore
Ithute haholoanyane
Papiso ea likhoele tse peli tsa DNA tse nang le lipheletso tse benyang khahlano le bokamorao bo lefifi bo nang le likere tse fokolang le meralo ea potoloho.

CRISPR/Cas9 ho lokisa mofuta oa RDEB

Ngaka Sergio López-Manzaneda, CIEMAT, Spain
Ithute haholoanyane
Setšoantšo sa kokoana-hloko e kenyang liphatsa tsa lefutso ka har'a sele, e bonts'a likaroloana tsa kokoana-hloko tse hokelang le ho fetisetsa DNA kapa RNA ka har'a sele e amohelang.

Ho ntlafatsa phano ea kalafo ea liphatsa tsa lefutso tsa RDEB

Ngaka Ángeles Mencia, CIEMAT, Spain
Ithute haholoanyane
Setšoantšo sa lipopae sa letoto la DNA

Hickerson 2 (2019)

Ngaka Robyn Hickerson, Univesithi ea Dundee, UK
Ithute haholoanyane
Setšoantšo sa lipopae sa letoto la DNA

Hubbard 1 (2017)

Lynne Hubbard, Sepetlele sa St Thomas ', London, UK
Ithute haholoanyane
Setšoantšo sa lipopae sa letoto la DNA

Liossi (2014)

Dr Christina Liossi, Univesithi ea Southampton, UK
Ithute haholoanyane